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Dr. Sands recommended using Sea Cumber & Coral Calcium with
CMOtm. Sea Cucumber (Beche-de-Mer) is a seabed dwelling marine
animal which feeds on microscopicalgae, absorbing nutrients
from the organic matter. Sea Cucumber has been used for
thousands of years by Asians as a culinary delicacy.
Tall Ships, Yankee Cutters, what precious cargo were they
taking to the Far East? Pearls or gold?
NO, it was Sea Cucumber!
The Chinese have treasured Sea Cucumber since ancient times for
prevention of disease and as a longevity tonic. Traditional
Chinese medicine commonly uses sea cucumber in treating
weakness, impotence, debility of the aged, constipation due to
intestinal dryness, frequent urination, and joint problems.
Western medicine is successfully using Sea Cucumber to treat
Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis,
and connective tissue disorders. Australia has approved the use
of sea cucumber as an over-the-counter treatment for arthritis
and the Japanese have a patent using sea cucumber chondroitin
sulfate for HIV therapy.
Beche de Mer (Sea Cucumber) is a marine animal related to
starfish and sea urchins containing mucopolysaccharides,
chondroitins, protein, vitamins A & C, riboflavin, niacin,
calcium, iron, magnesium, zinc, sodium, and carbohydrates. The
nutrient content of sea cucumbers is extremely broad, and total
identification of each innate constituent will probably never
be established. The University of Queensland Centre for Drug
Design conducted a series of chromotographs that displayed "an
enormous number of compounds". Some of the compounds identified
unique to the animal kingdom include two types of
triterpenoidal oligoglycosides, one type occurring with a
sulfate group and the other without. Molecules of this general
classification are abundant in the plant kingdom, but are quite
rare among animal tissues. Other compounds found in abundance
include analogues of monosaccharide structure and analogues of
sulfated mucopolysaccharide configuration.
Sea Cucumber has shown an ability to balance prostaglandins,
which regulate the inflammatory process. Sea cucumber has a
cartilaginous body that serves as a rich source of
mucopolysaccharides; mainly chondroitin sulfate, known for its
ability to reduce arthritis pain. As little as 3 grams per day
of the dried sea cucumber has been helpful in reducing
arthralgia (joint problems). Chondroitin's action is similar to
that of glucosamine sulfate, the main building block of
chondroitin.

Chondroitin building blocks can be repeated numerous times.
This is basically a glucose molecule (left potion) and
glucosamine molecule (right portion), which has been sulfated
(O3S, at the top). Long-chain sulfated polysaccharides, like
chondroitin, also inhibit viruses.
Russian, Japanese, and Chinese studies reveal that sea
cucumbers contain saponins (triterpene glycosides). These
compounds are structure similar to the active constituents of
ginseng, ganoderma, and other famous tonic herbs. Pharmacology
studies indicate anti-inflammatory and anticancer properties of
the sea cucumber saponins.
One of the sea cucumber saponins, representative of the
structures commonly found in these organisms.
In addition, the sea cucumber oil contains two
anti-inflammatory fractions. One fraction has fatty acids
characteristic of those found in fish; they can be used as a
substitute for fish oil in reducing inflammatory byproducts of
fat metabolism, and to nourish the brain and heart. The main
compounds of interest in fish oil are EPA (eicosapentaenoic
acid also found in sea cucumber, and DHA (docosahaenoic acid),
unique to fish:
 
Stereochemical representations of EPA (left) and DHA (right).
The double bond locations are different, causing a different
bending of the structures.
The other oil fraction is a mixture of branched chain fatty
acids, mainly 12-MTA (methyltetradecanoic acid). This compound,
and the more widely studied variant, 13-MTA, are potent
inhibitors of the 5-LOX (lypoxygenase) enzyme system. 5-LOX
inhibitors are one of the key areas of modern drug development,
with plans evolving to use the compounds in treatment of
asthma, ulcerative colitis, and arthritis. In addition,
cancer-inhibiting effects have been observed in preliminary
studies with prostate cancer cell lines and other human cancer
cells These fatty acids are thought to be produced by bacteria
that live within the sea cucumbers; they are also produced by
bacteria in other marine organisms, such as sponges and
tunicates.

Sample branched chain fatty acid found in sea organisms. The
central chain is a simple carbohydrate. These long chains can
interact with cell membranes.
The statements on this web site have not been evaluated by the
Food and Drug Administration. These products are not intended
to diagnose, treat, cure, or prevent any disease.
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